A team of scientists led by researchers at the University of Georgia has developed a new mouse model that closely mimics fetal brain abnormalities caused by the Zika virus in humans.
An UGA Assistant Professor of Genetics was recently awarded a grant from the National Institutes of Health to study neural tube defects in mice. The goal of Jianfu Chen’s project is to understand why neural tube defects, the second most common birth defect in humans, occur.
Esther van der Knaap, a professor of horticulture in the Institute of Plant Breeding, Genetics and Genomics, is exploring the regulation of fruit shape and size in tomatoes as well as in peppers. Much of her research focuses on the molecular genetic mechanisms of cell division and cell size underlying fruit formation, and her work seeks to help boost the yield and quality of fruit and vegetable crops for the agricultural industry.
Three UGA faculty members have been named recipients of the university’s highest early career teaching honor, the Richard B. Russell Awards for Excellence in Undergraduate Teaching.
A team of researchers that includes UGA scientists has identified many of the genetic changes that take place in burying beetles as they assume the role of parent. Their findings, published recently in the journal Nature Communications, may provide clues about the fundamental genetics of parenthood in insects and other animals.
When UGA researchers examined the genome of several different snake species, they found something surprising. Embedded in the reptiles’ genetic code was DNA that, in most animals, controls the development and growth of limbs—a strange feature for creatures that are famous for their long, legless bodies and distinctive slither.
Highlighted in the Editors’ Choice section of Science Signaling, our weekly journal from the publisher of Science magazine.
In a prime example of basic bacterial research informing human disease research, microbiologists have identified a potential mechanism for neurodegenerative diseases:
A team of scientists that includes University of Georgia genetics professor Nancy Manley have grown an organ for the first time in an animal.
Their success in inducing a mouse to grow a new thymus raises the possibility that scientists might be able to grow the organ in humans whose thymus is absent or impaired, or that their discovery might one day be used to grow important disease-fighting cells called T-cells outside the body.
The researchers created a thymus, a butterfly-shaped gland and vital component of the human immune system. Located beneath the breastbone in the upper chest, the thymus is responsible for producing T-lymphocytes, or T-cells, which help organize and lead the body’s fighting forces against threats like bacteria, viruses and even cancerous cells.
“We were all surprised by how well this works,” said Nancy Manley, professor of genetics in UGA’s Franklin College of Arts and Sciences and co-author of the paper describing their finding in Nature Cell Biology.
A team of scientists including researchers from the University of Georgia has grown a fully functional organ from scratch in a living animal for the first time. The advance could one day aid in the development of laboratory-grown replacement organs.
Scott Dougan and his research team are discovering new roles for a specific gene known as Max’s Giant Associated protein, or MGA. A little studied protein, MGA appears to control a number of developmental processes and also may be connected to cancer development.
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The thymus gland is a critical component of the human immune system that is responsible for the development of T-lymphocytes, or T-cells, which help organize and lead the body’s fighting forces against harmful organisms like bacteria and viruses.
The thymus gland is a critical component of the human immune system. It is responsible for the development of T-lymphocytes, or T-cells, which help organize and lead the body’s fighting forces against harmful organisms like bacteria and viruses. Nancy Manley, a professor of genetics in UGA’s Franklin College of Arts and Sciences and principal investigator for the project.
Most people don’t give much thought to the 10,000 taste buds on their tongue when they choose a chocolate chip cookie over an apple. UGA’s Hongxiang Liu thinks about these tiny sensory organs nearly every day.
Led by Karl Lechtreck, an assistant professor in the cellular biology department, a team of researchers used total internal reflection fluorescence microscopy to analyze moving protein particles inside cilia of Chlamydomonas reinhardtii, a widely used unicellular model for the analysis of cilia.